Архив рубрики: Здоровье Америка

Pfizer is ending the development of its potential once-daily pill treatment for obesity after venturing into the biggest and most expensive level of clinical testing.

The drugmaker said Tuesday that it would stop studying danuglipron after a participant in one of its trials experienced a possible drug-induced liver injury that ended once the person stopped taking the drug.

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Danuglipron was in phase three testing, which is generally the last phase of development before a company submits the potential treatment to government regulators for approval.

A company official said in a statement that Pfizer still plans to develop other potential obesity treatments in earlier stages of testing.

Read More: Weight-Loss Drugs Like Wegovy Are Linked to Hair Loss

Obesity treatments have become one of the more promising and lucrative sectors of drug development for pharmaceutical companies. Eli Lilly and Co.’s Zepbound, for instance, brought in nearly $5 billion in..

Dr. Peter Marks is the kind of health official both Democrats and Republicans used to admire. He served in the U.S. Food and Drug Administration (FDA) for 13 years, most of them as director of the Center for Biologics Evaluation and Research. There, Marks oversaw the critical process of reviewing and approving vaccines—like those against COVID-19—and biologic therapies, including gene- and cell-based treatments.

Marks earned trust and respect from academic and industry scientists as well for his emphasis on requesting the strongest evidence in evaluating new therapies, and for his willingness to support new technologies and approaches.

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But he did not last long in the new Trump Administration. On March 28, Marks resigned after he says he was pressed by Department of Health and Human Services (HHS) officials to come in line with skepticism about the safety and effectiveness of vaccines or be fired. He says his team was also asked by HHS to turn over se..

Hearing that you smell really stinks. If somebody wrinkles their nose and tells you it’s time for a shower, or subtly slides a mint your way, you might become defensive.

Yet that’s not the best way to proceed. “The first thing you should do is thank them,” says Sara Jane Ho, an etiquette expert and host of Netflix’s Mind Your Manners. Gratitude? For insulting your hygiene? That’s right. “Every time somebody tells you something, 50 people are thinking it but didn’t tell you,” Ho says. Hence the importance of uttering those two little words: thank you.

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Instead of stewing over the remark, reframe it as an opportunity for self-improvement, Ho advises. It’s essential not to take the feedback personally—though she acknowledges that’s easier said than done. “This is when you really see a difference between an insecure person and a secure person, because secure people don’t take critical feedback personally to their core,” she says. Those who struggle with ..

The Trump Administration’s move to withhold millions of dollars allocated for family planning services is affecting reproductive health care access in more than 20 states—including some that have made efforts to protect reproductive rights.

Enacted in 1970, Title X is the nation’s sole federally funded family planning program. The program doesn’t fund abortion services, but it does allocate more than $200 million annually for clinics that provide other forms of health care—including birth control, cancer screenings, and STI testing—for people from low-income households. Last week, the U.S. Department of Health and Human Services (HHS) said it is withholding funds from 16 organizations in the Title X program “pending an evaluation of possible violations” of federal civil rights laws and President Donald Trump’s Executive Order that said undocumented immigrants are barred “from obtaining most taxpayer-funded benefits.” Affected organizations received notices from HHS that their funds wo..

Strep infections are most well known for causing strep throat, which can be treated with antibiotics. But this type of bacteria can also cause more serious illnesses—even flesh-eating infections.

The bacteria responsible for the more serious infections are on the rise. In a report published April 7 in JAMA, researchers led by those at the U.S. Centers for Disease Control and Prevention (CDC) found that cases of invasive group A Streptococcus have been steadily increasing in the U.S. over the last decade, from 2013 to 2022. The data also showed that the bacteria are resistant to some commonly used antibiotics.

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Here’s what to know about the rise in strep infections.

What is group A strep?

Group A Streptococcus bacteria can cause illnesses from the common strep throat to sepsis, toxic shock syndrome, and necrotizing fasciitis (more commonly known as flesh-eating bacterial infections). Cases of strep throat aren’t considered invasive, but if the bacter..

TikTok is full of content creators claiming that eating certain foods helped them get pregnant—particularly those with polycystic ovary syndrome (PCOS), a hormone disorder that can affect fertility and metabolic health. But how truthful are those claims?

According to nutrition and fertility experts, while certain dietary plans may help some people with fertility, no one food or eating style is guaranteed to get you pregnant. The relationship between food and fertility is nuanced, they say, and people should be wary of any absolutist health claims they may encounter on social media.

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Videos making these claims “definitely can throw off our clients on their journey,” says McKenzie Caldwell, a registered dietitian nutritionist and founder of Feed Your Zest Nutrition & Wellness, a private practice that offers nutrition counseling for people who are dealing with reproductive health conditions.

“People are just sharing their personal experience vs. what ..

For an emergency medicine physician, a typical shift is a front-row seat to the worst days of people’s lives—a whirlwind of drama, frustration, quiet victories, devastating losses, and unfiltered humanity. And then, it’s onto the next patient’s room to do it all over again.

Maybe that’s why, as an emergency medicine attending physician in Chicago, I love The Pitt. My team’s work life is reflected onscreen, and watching the show evokes powerful emotions—at times, it feels as if the entire health care system rests on the shoulders of this small group of doctors and nurses. The show offers audiences a raw glimpse into a health care system on the brink. It shines a light on complex, urgent issues—hospital boarding, limited resources, and the mounting toll of trauma and mass casualty events—that affect both patients and the people working tirelessly to save them.

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I’ve heard that it’s an intense, gruesome watch for some. But as tense and uncomfortable as ..

Calvin Sun was a healthy 37-year-old when a full-body MRI scan showed a cyst in his kidney. Sun saw a urologist who was cautiously optimistic that it wasn’t cancerous and offered him a surgery appointment several weeks away to inspect the kidney and operate if necessary. “I was like, how about tomorrow?” Sun recalls.

As an ER doctor, Sun is used to decisive problem-solving. It’s the “right mindset” for undergoing a whole-body MRI, he says. “You have to be willing to take 100% responsibility for the consequences, good and bad.”

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Instead of traditional scans, like CTs or MRIs of a specific part of the body, full-body MRI scans require just an hour to image you from head-to-toe. Celebrities and influencers are holding them up as a pillar of preventive health to catch problems early on, wherever they’re hiding—before they become hard-to-treat diseases. Dwyane Wade, for example, recently credited a whole-body MRI with alerting him to an early-stage kidney ..

A new study found that the rates of pregnancy-related death in the U.S. increased by nearly 28% between 2018 and 2022, with large disparities based on state, race, and ethnicity.

The study, published in JAMA Network Open on April 9, analyzed four years of nationwide data from the U.S. Centers for Disease Control and Prevention. Researchers found that there were 6,283 pregnancy-related deaths during that time. The study determined that the rate increased from 25.3 pregnancy-related deaths per 100,000 live births in 2018 to a peak of 44.1 in 2021, before dropping slightly to 32.6 in 2022. The increase occurred across all the age groups that researchers analyzed, but people between the ages of 25 and 39 experienced the highest increase, according to the study.

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The study didn’t investigate why the rates of pregnancy-related death increased over the four-year period. But researchers noted in the study that the COVID-19 pandemic could have had an impact on..

Commenting on someone else’s hygiene is one of the more delicate conversation topics. You are, after all, critiquing a person’s body and health habits. But it’s a thorny road to go down: Hygiene issues can stem from medical or even financial issues. “Someone with bad breath could have something going on with their dental work—maybe they can’t afford to go to the dentist, so they’re stuck with something in their mouth that’s making it not smell so good,” says Katie Moore, a clinical psychologist in Irvine, Calif.

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Is it worth risking the potential awkwardness and saying something? Context matters, Moore says: If you’re never going to see the person again, she recommends staying mum. But if it’s a close friend or partner, and a recurrent problem? You’re probably not the first to notice, so you could be doing them a favor by bringing it up. The key is proceeding with tact—sometimes humor, sometimes concern. Talk to them face-to-face and privately, don’t a..