Which Weight-Loss Drug Works the Best?
As more doctors and patients turn to the latest weight-loss drugs, researchers are trying to figure out which drug is right for which patient—and at what point in their weight-loss journey.
Key to making those decisions is how effective the drugs are and which side effects people might experience while taking them.
A new study published in the New England Journal of Medicine and presented at the European Congress on Obesity provides some of those answers. Researchers report on a head-to-head trial comparing Wegovy (semaglutide), made by Novo Nordisk, to Zepbound (tirzepatide), made by Eil Lilly. The initial findings were released in Dec. by Eli Lilly, who funded the study. The current report includes more details on how the two drugs affected waist circumference and other measures, as well as their side effects.
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Among the 751 people randomly assigned to receive weekly injections of either the maximum dose of Wegovy or the maximum dose of Zepbound fo..